Maestro Brian Cefai is one of the few Maltese leading soloists who gained recognition for his talents in Malta and abroad where he performed most of his major works. He studied with Maltese and foreign voice teachers. In 1984 he was presented with the Accademia Del Mediterraneo award, after which he completed a three year course for perfection with Bulgarian tutor Dame Blagovesta Karnobatlova Dobreva and in England with world famous baritone Derek Hammond Straud. He studied theory of music and harmony with Maestro Carmelo Pace and orchestration and conducting with Maestro Anthony Chircop. After studying with Maestro Paolo Nani, Brian continued his studies in voice coaching, pedagogy and singing in London & Warwick as well as conducting at Warwick University with Colin Touchin. He obtained his fellowship in singing and teaching and this he achieved with Honours.

His repertoire includes various genres of music written in different eras, from lieder to oratorio and opera. In 1986 Brian made his debut in London at the Queen Elizabeth Hall and has since been a regular performer in England including venues such as Royal Albert Hall, Wigmore Hall, Leamington Spa, Barbican Centre, St. Paul’s Cathedral and the English National Opera (ENO). Apart from England, he performed in Austria, Czech Republic, Germany, Greece, Italy, Poland, Hungary, Denmark, The Netherlands, France, Sicily, Sweden, Scotland and Wales. He has sung with various personalities including the acclaimed Italian Soprano Katia Riccarelli. He has also joined forces with many tenors from the British Isles in concerts which included Placido Domingo, Sir Harry Secombe and José Carreras. Brian’s performances have included basically all the most important national events, such as the concert celebrating the birthday of her majesty the Queen mother of England, the summit between presidents Bush and Gorbachov, the United Nations Leaders concert at the Manoel Theatre, The CHOGM concert which was held in Malta, and for his holiness Pope John Paul II during his first visit to Malta, the Messiah being performed all over the world at the same time; and for her Majesty Queen Elizabeth’s Golden Jubilee amongst other important events. In 2010 Brian performed Mahler’s symphonic poem ‘Das Lied von der Erde’ along with the world renowned Birmingham philharmonic and Scottish Mezzo Soprano Karen Cargill, at a Festival held in Canterbury Cathedral. Brian’s operatic repertoire includes major roles in ‘La Bohème’, ‘La Traviata’, ‘Tosca’, ‘Lucia di Lammermoor’, ‘L’Amico Fritz’, ‘Tales of Hoffman’, ‘I Pagliacci’, ‘Faust’, ‘Un Ballo in Maschera’, ‘Macbeth’ and minor roles in ‘Aida’, ‘Norma’, ‘Carmen’ and many others. He has also performed in musicals ‘Jekyll and Hyde’ and conducted  Cats, Joseph and the Amazing Technicolour Dreamcoat, Oliver, Westside Story, My Fair Lady, Me & My Girl, Oklahoma & many others. Brian sang major roles in Maltese Operas including Charles Camilleri’s operas ‘Il- Fidwa tal-Bdiewa’ and ‘Il-Wegħda’ and in Carmelo Pace’s operas ‘Caterina Desguanez’, ‘Ipogeana’ and ‘I Martri’, and Joe Vella's ‘ir-Rewwixta’ and  'Il- Belt Rebbieħa.' Maestro Brian Cefai and Professor Charles Camilleri were so highly acclaimed for the Maltese Oratorio ‘Pawlu ta’ Malta’ that the Oratorio ended up on the shores of England and Wales where Brian sang excerpts of it in English.

In 1990 Brian founded The Amadeus Chamber Choir and has been its director ever since. Amongst the most important works under his baton, he has conducted thirty-two editions of the concert ‘A Prelude to Christmas’, and conducted the Orchestra of the Academy of Teatro Massimo di Palermo with the participation of his choir and foreign soloists in Mozart’s Requiem at the prestigious Cathedral of Monreale. Brian has conducted many major choral works, orchestral concerts, pantomimes, musicals, English operas and many important private concerts. In November 2013 Brian celebrated his 30th anniversary as a Tenor with a classical concert ‘Voce della Vita’. In October 2022, Brian was honoured with the award of ‘Ġieħ San Ġiljan’ by the St. Julian’s Local Council for his contribution to society.